Growth Inhibition of Clostridium Feseri by Carcinostatic Purine and Pyrimidine Analogs. I. Effect of Medium on Growth Inhibition.

نویسندگان

  • J G CAPPUCCINO
  • M GEORGE
  • P C MERKER
  • G S TARNOWSKI
چکیده

Clostridium feseri (chuavoei), ATCO-10092, grows well in a semi-synthetic basal medium devoid of purine bases and folic acid. Growth inhibition of this organism in such a medium by carcinostatic purine analogs is pronounced, and by pyrimidine analogs marked. Purines in the medium block the growth inhibition of Clostridium feseri by purine analogs. Greater agreement occurs between the growth inhibition of the organism and Adenocarcinoma 755 when carcinostatic purine and pyrimidine analogs are studied in purineless media as compared with complex thioglycollate medium.

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عنوان ژورنال:
  • Cancer research

دوره 24  شماره 

صفحات  -

تاریخ انتشار 1964